The study was carried out to assess the hydraulic performance of drip irrigation under indoor conditions. The treatments consist of three types of emitters (inline emitter, black and blue pressure compensating) and five levels of saline water (0.20, 0.35, 3.5, 5.0, and 5.75 dS/m). The hydraulic performance of the emitters was evaluated with reference to percentage of discharge reduction (R %), coefficient of discharge variation (CV %), Christiansen’s uniformity coefficient (CU %), scheduling uniformity (SU), emission uniformity (EU %), application efficiency (EA %) and clogging percentage (Pclog%). The results showed that the black type pressure compensating emitters recorded significa nt (P ≤ 0.05) decrease in R% and CV% for the five tested water qualities, and showed highest values of CU% for the well water. On the other hand, the inline emitters recorded the highest values of EU% and EA% for saline water of 5.0 ds/m salinity. The blue pressure compensating emitters showed the lowest clogging (Pclog%) for the five tested water qualities and lowest performance of EU% and EA% for the River Nile water 0.2, saline water 3.5, 5 and treated wastewater 5.75 dS/m, respectively. The black type pressure compensating and inline emitters showed no clogging. The study concluded that the emitter type and water quality are the main factors affecting the hydraulic performance of drip irrigation systems.